Manchester City vs Bayer Leverkusen Prediction, Lineups, Injuries and Team News

Manchester City are ready to host German giants Bayer Leverkusen in what should be a highly entertaining match in the UEFA Champions League on Tuesday, 25 November (2025). Manchester City are unbeaten in the league stages of the Champions League so far, having picked up 10 points from four games, being in third place, and the Cityzens are coming into this match with four wins in their last five matches as well. Erling Haaland is Manchester City's highest scorer in the Champions League so far, with five goals from four matches.

Bayer Leverkusen have recovered relatively well from a poor start to the 2025/26 campaign as they are in third place in the Bundesliga table, but the German side have only won one of their four matches in the Champions League so far. Bayer are in 21st place in the Champions League table, having five points from four games and Aleix Garcia is their top scorer in the competition with two goals so far. Now, we look at the Manchester City vs Bayer Leverkusen preview, and in the end, you can compare your match prediction with our Manchester City vs Bayer Leverkusen prediction.

Manchester City vs Bayer Leverkusen Match Info

• Match Info: Manchester City vs Bayer Leverkusen, UEFA Champions League
• Stadium Name: Etihad Stadium
• Kick-Off Timing: 8:00 PM GMT

Manchester City Team News

Pep Guardiola is having to deal with some nagging injuries in his Manchester City squad, especially when it comes to the dearth of some crucial options in his midfield position. Despite that, Guardiola will be eager to select his strongest XI as he aims for his side to get back to winning ways after the recent loss to Newcastle United. With that being said, here we look at the Manchester City vs Bayer Leverkusen predicted lineups as part of our Manchester City vs Bayer Leverkusen preview.

Manchester City Predicted Lineup (4-1-4-1):

Goalkeeper: Gianluigi Donnarumma

Defenders: Rico Lewis, John Stones, Josko Gvardiol, Rayan Ait-Nouri

Midfielders: Nico Gonzalez, Tijani Reijnders, Phil Foden

Forwards: Omar Marmoush, Jeremy Doku, Erling Haaland

Bayer Leverkusen Team News

Bayer Leverkusen boss Kasper Hjulmand is dealing with a number of nagging injuries in his squad, something that will not be making it any easy for him to guide his side to a win against the Cityzens. As many as five first-team players are going to be missing this crucial trip to Manchester, as Hjulmand needs to be smart with his team selection to help his side get a positive result from this game. Now, we look at the Bayer Leverkusen perspective of the Manchester City vs Bayer Leverkusen predicted lineups.

Bayer Leverkusen Predicted Lineup (3-4-2-1):
Goalkeeper: Mark Flekken

Defenders: Jonas Hoffaman, Jarrel Quansah, Loic Bade, Edmond Tapsoba, Alex Grimaldo

Midfielders: Nathan Tella, Aleix Garcia

Forwards: Martin Terrier, Ernest Poku, Patrik Schick

Manchester City vs Bayer Leverkusen injuries

Now, we look at the players who are going to be missing the Manchester City vs Bayer Leverkusen clash because of their injury troubles.

Manchester City gaffer Pep Guardiola is currently dealing with the absence of two crucial midfielders in Rodri and Mateo Kovacic. The former Ballon d'Or winner is dealing with fitness issues that he has to get over to start playing again, while Mateo Kovacic is a long-term absentee and will definitely be ruled out for this match.

On the other hand, Kasper Hjulmand is having to deal with a plethora of nasty injuries in his Bayer Leverkusen squad. Summer signing Lucas Vazquez is out with a muscle injury, as are hard-working players like Exequiel Palacios as well as Equi Fernandez. On top of all the injury troubles, Bayer Leverkusen midfielder Robert Andrich is also suspended for the upcoming match after being sent off in the 7-2 loss to PSG recently in the Champions League.

Manchester City vs Bayer Leverkusen Prediction

With a desperate Manchester City side facing a Bayer Leverkusen team who have shown major signs of improvement in recent months, this Champions League clash should be an eventful one. Even though Manchester City have home advantage and a terrorising attacking force, the German side aren't one to back out from the fight and will look to torment them on the transitions.

This upcoming clash at the Etihad Stadium should be an entertaining affair, where both sides should get plenty of goal-scoring chances. However, the sheer power of the Manchester City frontline and the energy they get from home fans should power them to a big win.

Predicted Scoreline: Manchester City 2-0 Bayer Leverkusen